Medical News

Prospective Evaluation of Unsuspected Pulmonary Embolism on Coronary Computed Tomographic Angiography
Jia CF et al. – Unsuspected pulmonary embolism (PE) was found in 0.9% of all patients undergoing coronary computed tomographic angiography (CCTA), and this kind of PE has its own characteristics compared with the typical PE from the literature. Radiologists should routinely analyze the pulmonary arteries in all patients undergoing CCTA, especially for older patients and the patients with atrial fibrillation (AF) or AF history and cardiac insufficiency....
Journal of Computer Assisted Tomography , 03/26/2012

18F-FDG-PET evaluation of treatment response to neo-adjuvant therapy in patients with locally advanced rectal cancer: A meta-analysis
Zhang C et al. – Fluor–18–deoxyglucose (FDG–positron emission tomography (PET) is valuable for predicting the response of rectal carcinoma to neo–adjuvant therapy, and early evaluation of response during the therapy may be more promising. However, additional studies using prospective clinical trials will be required to assess the clinical benefit of this strategy. ...
International Journal of Cancer , 03/26/2012

Platelet-Rich Fibrin Combined With a Porous Hydroxyapatite Graft for the Treatment of Three-Wall Intrabony Defects in Chronic Periodontitis: A Randomized Controlled Clinical Trial
Pradeep AR et al. – Treatment of intrabony defects with Platelet–rich fibrin (PRF) results in significant improvements of Clinical parameters compared with baseline. Hydroxyapatite (HA) when added to PRF increases the regenerative effects observed with PRF in the treatment of human three wall intrabony defects....
Journal of Periodontology, 03/27/2012

Association between long-term aspirin use and periodontal attachment level in humans: a cross-sectional investigation
Faizuddin M et al. – The results of this study suggest that low dose aspirin may reduce the risk of periodontal attachment loss. This hypothesis needs to be tested by larger sample sized prospective cohort studies....
Australian Dental Journal , 03/26/2012

Orbitomaxillary reconstruction using the layered fibula osteocutaneous flap
Shipchandler TZ et al. – The fibula osteocutaneous free flap, because of its design flexibility and ability to provide structural support, is an excellent reconstructive option for total maxillary defects, including those that involve the orbit.
Archives of Facial Plastic Surgery , 03/29/2012

Laparoscopic Sleeve Gastrectomy as a Stand-Alone Procedure for Morbid Obesity: Report of 1,000 Cases and 3-Year Follow-Up
Boza C et al. – Laparoscopic sleeve gastrectomy (LSG) seems to be a safe and effective surgical technique for morbid obesity as a stand–alone procedure.
Obesity Surgery , 03/26/2012

Dose Response to Vitamin D Supplementation in Postmenopausal Women
Gallagher JC et al. – A vitamin D3 dosage of 800 IU/d increased serum 25–(OH)D levels to greater than 50 nmol/L in 97.5% of women; however, a model predicted the same response with a vitamin D3 dosage of 600 IU/d. These results can be used as a guide for the RDA of vitamin D3, but prospective trials are needed to confirm the clinical significance of these results.
Annals of Internal Medicine, 03/27/2012

Vitamin D status: a review with implications for the pelvic floor
Parker–Autry CY et al. – This paper reviews current knowledge regarding vitamin D nutritional status, the importance of vitamin D in muscle function, and how insufficient or deficient vitamin D levels may play a role in the function of the female pelvic floor. .
International Urogynecology Journal , 03/26/2012

Eating patterns and lipid levels in older adolescent girls
Bradlee ML et al. – Healthy childhood eating patterns characterized by higher intakes of a variety of fruits, vegetables, whole grains, dairy, lean meat, poultry and fish are important modifiable predictors of lipid levels in late adolescence.
Nutrition, Metabolism & Cardiovascular Diseases, 03/30/2012

Body fat, abdominal fat and body fat distribution related to cardiovascular risk factors in pre-pubertal children
Dencker M et al. – Total body fat, abdominal fat and body fat distribution were all associated with higher composite risk factor scores for CVD in young children.
Acta Pediatrica, 03/30/2012

Comparison of alternate day atorvastatin treatment to daily treatment in maintaining LDL-Cholesterol targets in patients with variable coronary risk profile
Pattanaika S et al. – Alternate–day treatment of atorvastatin was inferior to daily treatment in maintaining the INCEP–ATPII goal.
Journal of Cardiovascular Pharmacology , 03/29/2012

Renal safety of intensive cholesterol-lowering treatment with rosuvastatin: A retrospective analysis of renal adverse events among 40,600 participants in the rosuvastatin clinical development program
treatment with rosuvastatin does not affect the risk of developing renal insufficiency or renal failure in patients who do not have advanced, pre–existing renal disease.
Atherosclerosis, 03/27/2012

Vorapaxar in the Secondary Prevention of Atherothrombotic Events
Morrow DA et al. – Inhibition of protease–activated receptor–1 with vorapaxar reduced the risk of cardiovascular death or ischemic events in patients with stable atherosclerosis who were receiving standard therapy. However, it increased the risk of moderate or severe bleeding, including intracranial hemorrhage.
New England Journal of Medicine, 03/28/2012

Treatment of functional chest pain with antidepressants: a meta-analysis
Wang W et al. – Antidepressant medications are associated with improvements in pain and psychological symptoms. The effects of factors including psychiatric co–morbidity, gender, age, ethnic group, and treating period on the outcomes should be checked further.
Pain Physician, 03/26/2012